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Atrial fibrillation patients on anticoagulation therapy don't require clopidogrel (Plavix) plus aspirin following stenting and it's aspirin, not clopidogrel, that should be omitted, researchers said.

In a small, randomized trial patients taking warfarin plus clopidogrel had significantly less bleeding than those randomized to clopidogrel, aspirin, and an anticoagulant -- 19.5 percent versus 44.9 percent HR 0.36 (95 percent CI 0.26 to 0.50 P<0.001), reported Willem Dewilde, from TweeSteden Hospital in The Netherlands, and colleagues.

Moreover, skipping aspirin did not increase mortality, stent thrombosis, or MI, Dewilde said here at the European Society of Cardiology meeting.

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