More Blood, Worse Outcomes For Kids' Heart Transplants

Fri, 02/24/2012 - 3:45am
Todd Neale

In pediatric heart transplantation, increasing amounts of blood transfused appears to be associated with worsening outcomes, researchers found.

After adjustment for other established risk factors for poorer transplantation outcomes, higher total amounts of red blood cells transfused were associated with a longer stay in the intensive care unit, more days intubated, and a higher inotrope score (P<0.05 for all), according to Kimberly Howard-Quijano, MD, of the University of California Los Angeles.

In addition, the patients who had a major adverse event following the operation received significantly more blood than those who did not, she reported at the Pediatric and Congenital Cardiovascular Disease meeting here.

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