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Stereotactic Surgery Plus tPA Shrinks Clots In Stroke

Mon, 02/06/2012 - 7:53am
Todd Neale

Reducing the size of an intracerebral hemorrhage (ICH) through a minimally invasive surgical technique and thrombolytic therapy may help improve clinical outcomes, a phase II trial showed.

Compared with medical therapy, aspirating the clot with a catheter and directly injecting tissue plasminogen activator (tPA) through a small hole in the skull increased the percentage of patients who had a good functional recovery from 28 to 38 percent by six months, according to Daniel Hanley, MD, of Johns Hopkins University in Baltimore.

Mortality, bleeding, and infection rates all remained below the safety thresholds, Hanley reported at the American Stroke Association's International Stroke Conference here.

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