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Limited Surgery Better For Small Kidney Tumors

Tue, 05/22/2012 - 7:39am
Charles Bankhead

ATLANTA -- Mortality risk decreased by more than 40 percent in patients whose early-stage kidney cancer was treated by partial versus radical nephrectomy, analysis of a National Cancer Institute (NCI) database showed.

Patients younger than 75 had a 53 percent reduction in the mortality hazard when they underwent nephron-sparing surgery instead of radical nephrectomy, and a higher comorbidity score was associated with an even greater mortality benefit.

"The magnitude of the benefit increased with follow-up," Hung-Jui Tan, MD, of the University of Michigan in Ann Arbor, said here at the American Urological Association meeting. "The absolute difference increased from about 5 percent at 2 years to as much as 16 percent with 8 years of follow-up."

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