Brain Aneurysm Characteristics Predict Rupture

Fri, 06/29/2012 - 7:24am
Nancy Walsh

Size, location, and shape of cerebral aneurysms can help predict whether rupture is likely to occur, a Japanese study found.

Compared with aneurysms 3 to 4 mm in size, 7-to-9-mm lesions had a hazard ratio for rupture of 3.35 (95 percent CI 1.87 to 6, P<0.001), according to Akio Morita, MD, PhD, of the University of Tokyo, and colleagues.

And compared with lesions in the middle cerebral arteries, the hazard ratios were 2.02 (95 percent CI 1.13 to 3.58, P=0.02) for those in the anterior communicating artery and 1.90 (95 percent CI 1.12 to 3.21, P=0.02) for those in the internal carotid-posterior communicating artery, the researchers reported in the June 28 issue of the New England Journal of Medicine.

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