CABG Plus Valve Replacement Tied to Added Risk

Tue, 02/19/2013 - 9:45am
Todd Neale

Doing aortic valve replacement and coronary artery bypass grafting (CABG) at the same time led to worse outcomes than valve replacement alone, but the difference was attributed to patient characteristics, researchers found.

Without accounting for patient differences, those who underwent both aortic valve replacement and CABG had worse survival at every time point from 30 days (97.6% versus 98.7%) to 10 years (43% versus 59%), as well as higher rates of septicemia, renal failure, prolonged ventilation, and atrial fibrillation in the hospital, according to Tomislav Mihaljevic, MD, of Cleveland Clinic Abu Dhabi in the United Arab Emirates, and colleagues.

In a propensity-matched analysis in which comorbidity burden was similar in each group, however, the survival rate was not different between the two groups at 1 year (93% in each group), 5 years (80% in each group), or 10 years (55% in the valve replacement alone group, and 50% in the valve+CABG group), the researchers reported in the Feb. 26 issue of the Journal of the American College of Cardiology.

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