Woman's Radical Procedure Transforms Liver Into Super Organ

Tue, 02/05/2013 - 9:11am
Sydney Lupkin

Food started to bother Allison Sarver when she was 18 years old, giving her attacks of nausea and pain after meals. By the time she was 24, she would sneak out of her office after lunch to lie down in her car until the attacks passed. By the end of that year, she was no longer able to eat or drink anything and had to rely on intravenous feeding to survive.

After years of alternately ignoring the symptoms and getting misdiagnosed with ailments such as irritable bowel syndrome, a doctor in Philadelphia finally told Sarver she had chronic pancreatitis, meaning her pancreas -- the organ that produces insulin and other enzymes necessary for digestion -- had become scarred and enflamed. Unable to eat without pain, Sarver lost 30 pounds in two months and was found to be deficient in vitamins A, B, D and E.

While grateful for a diagnosis, getting treatment for her pancreatitis remained another matter. "I was told, 'If we can't help you, no one else can help you,'" she said, referring to her team of doctors. "I thought, 'There has to be a place that does [treats] this.'"

An Internet search led Sarver to the pancreas clinic at Johns Hopkins Hospital in Baltimore, which specialized in pancreatitis.

They had been performing a surgery on some of their patients that involved removing the entire pancreas, extracting its insulin-producing cells -- called islets -- and moving them to the patient's liver. The liver would then take over the job of producing insulin to regulate blood glucose levels, and the patient would take enzyme pills to fulfill the pancreas's remaining jobs, which include aiding in the digestion of fats, carbohydrates and protein.

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