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Incisionless Option For Stomach Ulcer Bleeding

Wed, 04/07/2010 - 5:39am

According to early clinical evidence from a safety study, a new endoscopic spray from Cook Medical may offer a new surgery-free procedure for treating acute bleeding of peptic ulcers. The early results, collected at the Chinese University of Hong Kong by lead investigators Dr. Joseph Sung of the Chinese University and Dr. Sam Giday of Johns Hopkins University, suggest this as an alternative to endoscopic and surgical intervention for major gastrointestinal (GI) bleeds.

“Peptic ulcer bleeds are medical emergencies,” said Dr. Giday. “This hemostatic spray shows promise for a faster, easier and less invasive procedure than currently available treatment modalities, which requires expert precision and a certain degree of endoscopic expertise.”

The hemospray, a proprietary powder with unique clotting abilities, can be sprayed directly onto a bleeding peptic ulcer through the channel of an endoscope guided down a patient's throat and into the stomach. In the safety study to date, the spray has been delivered to ten patients with acute GI bleeding. Patient bleeding was controlled in nine of 10 patients observed in the study, and after 72 hours eight patients were released with no apparent signs of re-bleeding.

A total of 20 patients will be enrolled in this initial study, the results of which will be used to decide whether further clinical trials will be conducted. The investigators expect to release final results of the study at the 2010 Digestive Disease Week conference in New Orleans in May.

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