Researchers at Thomas Jefferson University in Philadelphia have found that colonoscopy preparation drugs administered the same day as the procedure are equally effective to those given the night before and the morning of the procedure, but result in less complaints of side effects such as abdominal pain, sleep loss and workday interference.
The study compared results between 116 colonoscopy patients given a split dosage of colon preparation the night before and morning of their colonoscopy, and those given the colonoscopy preparation solely the morning of the procedure. The study shows that both treatments are clinically equal, according to primary investigator David Kastenberg, MD, Department of Gastroenterology and Hepatology at Jefferson Medical College of Thomas Jefferson University and his co-authors. The study is available in the online edition of the American Journal of Gastroenterology.
The American College of Gastroenterology has endorsed split dosing, which means patients experience the side effects of a colon prep at night and on the morning of the procedure, he said. “The real advantage of the morning prep is it has less interference on the patients' quality of life,” said Kastenberg.