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Patent For Implantable Technology Could Be A Game-Changer

Fri, 11/11/2011 - 4:45am

The University of Rochester Medical Center (URMC) has received a U.S. patent for a medical device technology that could revolutionize the way that physician’s monitor the health of their patients. The device – which consists of an implantable “living chip” – is designed to give doctors real time information on their patients’ health and, more importantly, alert them to a change in their condition.

The technology consists of a chip that holds the potential to identify physiologic and chemical changes in the body. This personalized-medicine technology uses live cells, which are engineered to live in and function as part of the miniature electronic chip. A wireless biosensor is placed within and around blood vessels and nerves to monitor surrounding tissues or organ systems and detect changes, which then triggers a message to a wireless device to alert the patient – or their physician – early on about a problem.

The potential application of the technology is extensive. The bio-chip could be used in patients with heart failure to detect changes in blood protein levels at an early stage, prompting the physician to alter medications to correct the problem more quickly. The device could also be used by researchers to monitor the effectiveness and safety of experimental drugs or to command other implanted devices – such as a wireless defibrillator/pacemaker or insulin pumps.

“This technology has the potential to make dramatic changes to how we practice medicine,” said Spencer Rosero, M.D., the URMC cardiologist who developed the technology behind the device. In 2005, Rosero founded Physiologic Communications and the company currently holds the URMC license for the technology. Physiologic Communications is in the process of being acquired by Raland Therapeutics, a Perinton-based firm that focuses on interventional medicine and therapeutic devices. 

The merger and patent now provide the technology with new resources and the intellectual property protection necessary to attract investment and continue research and development with the goal of beginning to test the device in people within the next five years. The technology will also help reduce the cost of drug development in early stage, pre-clinical evaluations of medicines allowing for better data results when used in the laboratory. This technology will be fast tracked using a 36-month goal for use in drug testing and development.

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