Low LDL May Spell Trouble In Bariatric Surgery

Tue, 05/21/2013 - 12:23pm
Nancy Walsh

Among factors that predicted the likelihood that patients undergoing bariatric surgery would experience postoperative cardiopulmonary complications were low levels of high-density lipoprotein (HDL) cholesterol and high levels of C-reactive protein, a researcher reported here.

In a cohort of 1,634 patients who had bariatric surgery during a 10-year period, the odds of a cardiopulmonary complication occurring within 3 months of the procedure were more than doubled among those whose cardioprotective HDL was at or below 40 mg/dL at baseline (odds ratio 2.4, 95% CI 1.11 to 5.19), according to Trit Garg, a medical student at Stanford University in Stanford, Calif., and colleagues.

Having high-sensitivity C-reactive protein of 11 or higher also was predictive (OR 2.22, 95% CI 1.05 to 4.67), suggesting that systemic inflammation may contribute to disease burden and risk of complications.

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