The Autosuture ENDO STITCH suturing device is designed to simplify endoscopic (running or interrupted) suturing and intracorporeal knot tying. The ENDO STITCH instrument, with its integral needle and suture enables a surgeon to perform most endoscopic procedures without struggling with loose needles and suture. A wide range of available suture materials makes it suitable for use in most endoscopic procedures, including Nissen Fundoplication, gastric bypass, and myomectomy. All needles and sutures are housed in convenient, ready-to-load cartridges. The shaft of the ENDO STITCH 10-mm instrument is 36 cm long to provide enhanced access to the tissue site. The large 4-mm tissue gap, combined with the jaw' s ability to compress tissue, allows the ENDO STITCH device to accommodate a wide variety of tissue thicknesses, from thin, delicate tissue to tissue requiring the application of a 4.8-mm staple.