Melbourne researchers have revealed the critical importance of highly specialised immune cells, called natural killer cells, in killing melanoma cells that have spread to the lungs. The team, from the Walter and Eliza Hall Institute, also found natural killer cells were critical to the body's rejection of donor bone marrow transplants and in the runaway immune response during toxic shock syndrome.
A recent study of an ultrasound-guided regional anesthesia technique, called femoral nerve block, shows that it leads to less opioid use and allows the majority of patients to go home within hours of surgery. "Our goal with this technique is to reduce pain, which improves patient outcomes and patient satisfaction," said Tarun Bhalla, MD, director of Acute Pain and Regional Anesthesia at Nationwide Children's Hospital.
For the first time in the United States, doctors at Henry Ford Hospital used a minimally invasive procedure to replace a failing, hard-to-reach heart valve with a new one – and placed it just outside the heart. Henry Ford is the first hospital in the United States to perform the unique, transcatheter tricuspid valve replacement, which was pioneered in Germany.
A surgeon at University of Louisville Hospital, part of KentuckyOne Health, recently performed an extended endoscopic skull-based surgery of the brain, a unique surgery of its kind in Kentucky. This approach reduces risks and recovery times for the patient who would otherwise need a craniotomy, which requires temporary removal of a bone flap from the skull to access the brain and brain retraction to reach the tumor.
In creating an adhesive patterned after glue produced by the lowly underwater sandcastle worm, researchers reported they may have solved the problem of premature births that sometimes result from fetal surgery. It also could open up numerous opportunities to safely perform more complex fetal surgeries in the future.
A multicenter study including University of Kentucky researchers found that a new nerve repair technique yields better results and fewer side effects than other existing techniques. Participants with nerve injuries were randomized into either conduit or allograft repair groups. Following the surgeries, independent blind observers performed standardized assessments at set time points to determine the degree of sensory or motor recovery.
A new Mayo Clinic study found that 1 in 5 patients who went to the emergency room with gallbladder pain and were sent home to schedule surgery returned to the ER within 30 days needing emergency gallbladder removal. The surgical complication rate rises with the time lag before surgery, the researchers say.
A stroke therapy using stem cells extracted from patients' bone marrow has shown promising results in the first trial of its kind in humans. Four out of five patients had the most severe type of stroke: only four percent of people who experience this kind of stroke are expected to be alive and independent six months later. In the trial, all four of these patients were alive and three were independent after six months.
Scientists report that neurons derived from human induced pluripotent stem cells (iPSC) and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons extending virtually the entire length of the animals' central nervous system. Scientist Paul Lu, PhD, said the axons extended through the white matter of the injury sites, frequently penetrating adjacent gray matter to form synapses with rat neurons.
Mutations in a gene that helps regulate when genes are switched on and off in cells have been found to cause rare cases of Wilms tumor, the most common kidney cancer occurring in children. The researchers studied the genes of 35 families with more than one case of Wilms tumor, recruited to the study through a network of collaborators from across the world.
ConforMIS, a medical device company providing the only truly customized total knee implant systems for patients, today announced results from two in vivo clinical studies comparing the motion patterns of patients treated with ConforMIS’ iTotal® versus off-the-shelf knee implants. The studies involved the first-ever use of an advanced real-time mobile x-ray fluoroscopy system designed to measure a wider range of natural movements.
Recent studies have shown that transplanting induced pluripotent stem cell-derived neural stem cells (iPS-NSCs) can promote functional recovery after spinal cord injury in rodents and non-human primates. However, a serious drawback to the transplantation of iPS-NSCs is the potential for tumor growth, or tumorogenesis, post-transplantation.
A team of researchers have created a biodegradable biomaterial that is inherently antioxidant and can be used to create elastomers, liquids that turn into gels, or solids for building devices or implants that are more compatible with cells and tissues, reducing inflammation or rejection.
Researchers have identified two previously undescribed radiological signs of potentially life-threatening slippage of laparoscopically adjustable gastric bands. Adding widespread knowledge of the new signs—inferior displacement of the superolateral band margin by more than 2.4 cm from the diaphragm and the presence of an air-fluid level above the band will aid in diagnosing affected bariatric patients.
Previously, “if the portion removed during the first surgery came back positive for cancer, a second surgery was needed to remove the rest of the thyroid. The molecular testing panel now bypasses that initial surgery, allowing us to go right to fully removing the cancer with one initial surgery. This reduces risk and stress to the patient, as well as recovery time and costs.”
Surgeon Vandana Thoravade said Ashik Gavai suffered complex odontoma, a rare condition in which a tumor grows under a gum and creates smaller tooth-like growths called denticles. He said the team of dental surgeons took seven hours to remove all the denticles.
Doctors had a simple goal when they first saw how a football-size rock thrown from an interstate overpass had shattered Sharon Budd's skull — keep her alive. Screws, bolts and plates now hold together the face of the seventh-grade teacher from Uniontown, Ohio.
The fundamental aspects of enhanced recovery after surgery (ERAS) programs are guidelines that focus on education, fluid management, minimal incision length, decreased use of tubes and drains, opioid-sparing analgesia, early mobilization and eating after surgery.
For scientists and researchers who are developing new treatments for disease, data is power. For patients, data can mean empowerment. Devices that track health indicators are readily available and in use to track heart rate, blood pressure, blood sugar and even respiratory rate and body temperature ...
A newly published peer-reviewed paper states that Stretta therapy is a safe and effective treatment option for gastro esophageal reflux disease (GERD). The paper states that Stretta addresses a significant unmet need where patients receive inadequate control from PPI therapy, or find surgery an undesirable option.
The cost-effectiveness of robotic devices for high-volume surgeries, such as large joint reconstruction and spinal fusion, hasn't been justified yet. Furthermore, GlobalData says that the current economic climate and reimbursement hindrance for computer-assisted joint replacements have resulted in many hospitals feeling reluctant to embrace these modern technologies.
"... extreme back pain due to spinal tumors degrades quality of life, and until now, limited minimally invasive procedural options ... have been available,” said Nam D. Tran, M.D., and Ph.D., neuro-oncology surgeon. “This multi-center study validates t-RFA as a treatment option that provides rapid, lasting pain relief without the need to interrupt the patient’s primary cancer therapy.”
Google Glass is being tested for use in the emergency room and during surgeries...
Scientists at Brigham and Women's Hospital have developed a scalable, next-generation platelet bioreactor to generate fully functional human platelets in vitro. The work is a major biomedical advancement that will help address blood transfusion needs worldwide...