Francis J. Schanne, M.D., F.A.C.S. of the Urologic Surgical Associates of Delaware and The Wills Eye Surgery Center in Wilmington discusses InterStim Therapy and how it has helped his patients. InterStim therapy is a pacemaker for the bladder used to reestablish appropriate nueromodulation of the bladder. The device works by using a stimulator device in the buttocks to stimulate the S3 nerve root in the pelvis. This is the primary nerve root for bladder function. Stimulating the sacral nerve number 3 (S3) nerve root with the InterStim device can result in dramatic decrease in frequency, urgency and urge incontinence. InterStim therapy can also improve bladder emptying and result in decreasing post void residuals and therefore decreasing urinary tract infections and the other complications of incomplete bladder emptying. InterStim therapy can also be used to treat interstitial cystitis and pelvic pain. Outcomes for interstitial cystitis and pelvic pain are not as predictable as outcomes for frequency, urgency and urge incontinence.